English name: 6-ThioxanthineEnglish alias: 2H-Purin-2-one,1,3,6,7-tetrahydro-6-thioxo-;3,6-Dihydro-6-thioxo-9H-purine-2(1H)-one;6-Mercaptoxanthine;6-Thioxo-1,3,6,7-tetrahydro-purin-2-one;6-Thioxo-1,3,6,9-tetrahydro-2H-purin-2-one;Imidazolo[4,5-d]pyrimidin-6(5H)-one,4,7-dihydro-4-thione-;Xanthine,6-thio-;2-HYDROXY-6-THIOPURINEchemical CAS NO. 2002-59-7Molecular formula: C5H4N4OSMolecular weight: 168.18Melting point: 300°CDensity: 1.534(estimate)Refractive index: 1.6390(estimate)Storage condition： 2-8°CAppearance and properties: Light Yellow to Dark Beige liquid6-Thioxanthine is a chemical compound that belongs to the xanthine family. It is a sulfur-substituted derivative of xanthine and is structurally similar to caffeine and theobromine.6-Thioxanthine is a purine alkaloid and is found in trace amounts in certain plants, such as tea leaves and cocoa beans. It is also a metabolite of the drug pentoxifylline, which is used to improve blood flow in patients with peripheral vascular disease.In terms of its pharmacological effects, 6-thioxanthine is a weak antagonist of adenosine receptors, particularly the A1 and A2A subtypes. Adenosine receptors are involved in various physiological processes, including regulation of sleep, cardiovascular function, and inflammation. By blocking these receptors, 6-thioxanthine may have potential therapeutic applications in the treatment of asthma, cardiovascular diseases, and other conditions.However, further research is needed to fully understand the pharmacological properties and potential therapeutic uses of 6-thioxanthine.
